diff --git a/CHANGELOG.md b/CHANGELOG.md
index bcd5653686..488d6007f3 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -2,6 +2,10 @@
 
 ## Unreleased
 
+### Fixes
+
+- Do not allow multiple `sentry.proguard-uuid` metadata to be set in Android manifest ([#4647](https://github.com/getsentry/sentry-dotnet/pull/4647))
+
 ### Dependencies
 
 - Bump Java SDK from v8.22.0 to v8.23.0 ([#4586](https://github.com/getsentry/sentry-dotnet/pull/4586))
diff --git a/src/Sentry/buildTransitive/Sentry.targets b/src/Sentry/buildTransitive/Sentry.targets
index c33ed0efbf..08a63ffdcf 100644
--- a/src/Sentry/buildTransitive/Sentry.targets
+++ b/src/Sentry/buildTransitive/Sentry.targets
@@ -271,11 +271,12 @@
     <Warning Condition="'$(_SentryCLIExitCode)' != '0'" Text="Sentry CLI could not upload debug files." />
   </Target>
 
-  <Target Name="UpdateAndroidMetadata" BeforeTargets="GetAssemblyAttributes"
-          Condition="
-            $([MSBuild]::GetTargetPlatformIdentifier('$(TargetFramework)')) == 'android'
+  <!-- Only for the application assembly: https://github.com/getsentry/sentry-dotnet/pull/4647 -->
+  <Target Name="UpdateAndroidMetadata"
+          BeforeTargets="GetAssemblyAttributes"
+          Condition="'$(AndroidApplication)' == 'True'
+            and $([MSBuild]::GetTargetPlatformIdentifier('$(TargetFramework)')) == 'android'
             and '$(SentryUploadAndroidProGuardMapping)' == 'true'">
-
     <ItemGroup>
       <AssemblyAttribute Include="Android.App.MetaData">
         <_Parameter1>io.sentry.proguard-uuid</_Parameter1>